Effects of Traditional Chinese Medicine as an Adjuvant Therapy on Inflammatory Factors, Vascular Endothelial Function and Growth Factors in Diabetic Retinopathy Patients

Abstract

Objective To explore the effects of traditional Chinese medicine as an adjuvant therapy on inflammatory factors, vascular endothelial function and growth factors in diabetic retinopathy patients. Methods A total of 96 diabetic retinopathy patients were selected as the research subjects, and they were randomly divided into control group and observation group. The control group was treated with pan-retinal photocoagulation, while the observation group was treated with Chinese medicine as an adjuvant therapy combined with pan-retinal photocoagulation. The clinical efficacy, inflammatory factors, vascular endothelial function and growth factor levels of the two groups were compared before and after treatment. Results After treatment, the total effectiveness rate of the observation group was significantly higher. After treatment, the serum levels of interleukin, hypersensitive C-reactive protein and tumor necrosis factor-α in the two groups were significantly lower than those of before treatment, with the parameters in the observation group sharply lower. After treatment, the levels of endothelin-1, vascular endothelial growth factor and angiopoietin-2 in the two groups were noticeably lower than those of before treatment, and vascular endothelial diastolic function was significantly higher. Moreover, the levels of the ET-1, VEGF, Ang-2 in the observation group were significantly lower, and FMD was greatly higher. Conclusion The adjuvant treatment with traditional Chinese medicine can greatly improve the clinical efficacy of diabetic retinopathy, alleviate the inflammatory response, improve vascular endothelial function and inhibit the formation of new blood vessels.