Application of Tongbian Scraping Combined with Suhuang Zhike Capsule in Chronic Obstructive Pulmonary Disease

Xueqin Hou; Zijie Yin

doi:10.62767/jecacm601.2683

Authors

Xueqin Hou Hangzhou Dinglan Clinic of Traditional Chinese Medicine, 310000 Hangzhou, Zhejiang, China Author
Zijie Yin Shangcheng District Jianqiao Subdistrict Community Health Service Center, Airport Road No. 238-6, Shangcheng District, 310009 Hangzhou, China Author

DOI:

https://doi.org/10.62767/jecacm601.2683

Keywords:

Tongbian scraping, Suhuang Zhike capsule, chronic obstructive pulmonary disease, lung function

Abstract

Objective: This study investigates the application of Tongbian scraping combined with Suhuang Zhike capsule in chronic obstructive pulmonary disease (COPD). Methods: 43 patients with COPD treated with Tongbian scraping combined with Suhuang Zhike capsule from January 2023 to June 2023 in our hospital were allocated into the observation group, and 53 patients with COPD treated with Suhuang Zhike capsule were assigned into the control group during the same period. The clinical efficacy and adverse reactions in the two groups were compared, and the changes of traditional Chinese medicine (TCM) syndrome score, lung and immune functions, and 6-min walking distance were observed before and after treatment. Results: The total effective rate of clinical efficacy in the observation group was higher than that in the control group (p < 0.05). After treatment, TCM syndrome score, COPD evaluation test score, and CD8⁺ level were decreased in both groups (p < 0.05), and these in the observation group were lower than those in the control group (p < 0.05). The forced expiratory volume in the first second (FEV₁), the predicted percentage of FEV₁ in FEV, the levels of CD4⁺ and CD4⁺/CD8⁺, and 6-min walking distance in both groups were elevated (p < 0.05), and these in the observation group were increased when compared with those in the control group (p < 0.05). There was no significant difference in nausea, vomiting, constipation, dizziness, and total adverse reactions between the two groups (p > 0.05). Conclusions: Tongbian scraping combined with Suhuang Zhike capsule has good clinical effect in the treatment of COPD, which can alleviate clinical symptoms, improve lung and immune functions, and enhance the activity tolerance, with good safety.

References

Rabe K, Watz H. Chronic obstructive pulmonary disease. Lancet 2017; 389(10082): 1931-1940.

Hattab Y, Alhassan S, Balaan M, et al. Chronic Obstructive Pulmonary Disease. Critical Care Nursing Quarterly 2016; 39(2): 124-130.

Singh D. Pharmacological treatment of stable chronic obstructive pulmonary disease. Respirology 2021; 26(7): 643-651.

Zhen X, Deng P, Yan X. Clinical study of Yupingfeng powder combined with traditional Chinese medicine lung rehabilitation treatment for stable COPD patients. Journal of China Prescription Drug 2023; 21(1): 141-145.

Kang X, Fu J, Gao N, et al. Relationship between Traditional Chinese Medicine Dialectical Classification and Pulmonary Function and Inflammatory Indexes in Patients with Stable COPD. Journal of Sichuan Traditional Chinese Medicine 2022; 40(12): 48-52.

Gu C, Peng W, Wang Z, et al. Suhuang Zhike Capsules for the Treatment of Cough Variant Asthma: A Meta-analysis. Evidence-Based Complementary and Alternative Medicine 2020; 2020: 9485746.

Ma M, Yang Q, Xu H, et al. Observation on the effect of Hufu Tongbian scraping in patients with cold-dampness obstruction rheumatoid arthritis. Journal of Nursing 2023; 38(20): 52-55.

Wang S, Cui H, Duan Z, et al. Application of Tongbian scraping combined with pain point massage in elderly shoulder periarthritis. Chinese Journal of Gerontology 2023; 43(9): 2139-2142.

Ma Y, Zhao Y, Lin Y, et al. Effect of auricular Tongbian scraping combined with auricular point sticking on insomnia after hormone shock therapy for thyroid-related eye diseases. Chinese Journal of Integrative Nursing 2022; 8(12): 199-203.

Liu N, Wen K, Su S, et al. Nursing experience of Li's Hufu copper needle scraping treatment for chronic obstructive pulmonary disease. Journal of External Therapy of Traditional Chinese Medicine 2018; 27(6): 47-48.

Chinese Society of Aspiration of Chinese Medical Association. Guidelines for the Diagnosis and Treatment of Chronic Obstructive Pulmonary Disease (2013 Revision). Chinese Journal of Tuberculosis and Respiratory Diseases 2013; 36(4): 225-264.

Pulmonary Disease Professional Committee of the Internal Medicine Branch of the Chinese Society of Traditional Chinese Medicine. Diagnostic Criteria for Chinese Medicine in Chronic Obstructive Pulmonary Disease (2011 Edition). Journal of Traditional Chinese Medicine 2012; 53(2): 177-178.

Zhang L. The effect of Suhuang Zhike Capsule on serum indicators, CAT scores, and lung function in patients with acute exacerbation of chronic obstructive pulmonary disease. Modern Diagnosis and Treatment 2023; 34(3): 345-347.

Lin Z. Significance of CAT, 6MWT and pulmonary function tests in the assessment of the condition of elderly patients with moderate-to-severe COPD in the stabilized period. Modern Diagnosis and Treatment 2018; 29(16): 2638-2640.

Zhang D, Hong X, He J. Effects of Suhuang Zhike Capsules on Lung Function and Airway Remodeling in Patients in Stable Stage of Chronic Obstructive Pulmonary Disease. New Chinese Medicine 2023; 55(11): 86-89.

Dai L, Zhuang Y, Lv H, et al. Effectiveness and safety of Suhuang Zhike capsule as adjuvant treatment for acute exacerbation of chronic obstructive pulmonary disease: a systematic review and meta-analysis. Journal of Traditional Chinese Medicine 2023; 43(2): 231-238.

Ye X. Progress in the study of chemical composition and pharmacological effects of commonly used drug pairs of ephedra. Traditional Chinese Medicinal Research 2021; 34(3): 57-62.

Liang S, Meng X, Wang Z, et al. Polysaccharide from Ephedra sinica Stapf inhibits inflammation expression by regulating Factor-β1/Smad2 signaling. International Journal of Biological Macromolecules 2018; 106: 947-954.

Ju K, Zhao L. The research progress peucedanum decursivum chemical ingredients and pharmacological effects. Inner Mongol Journal of Traditional Chinese Medicine 2017; 36(3): 142-143.

He Y, Hao E, Xie J, et al. Research process on pharmacological effect and substance basis of Perilla frutescens. Chinese Herbal Medicines 2018; 49(16): 3957-3968.

Xiao X, Wang H, Ruan H. Research Progress on Chemical Constituents and Pharmacological Activities of Pipaye (Eriobotryae Folium). Guiding Journal of Traditional Chinese Medicine and Pharmacology 2019; 25(21): 60-66.

Chen T, Deng W. Clinical Study of Copper Scraping Combined with Auricular Point Pressing Beans in the Treatment of Chronic Obstructive Pulmonary Disease. Medical Innovation of China 2023; 20(14): 80-84.

Chen T, Deng W. Clinical study on treating chronic obstructive pulmonary disease with Tongbian Guasha combined with ear-point pressure Dou. Medical Innovation of China 2023; 20(14): 80-84.

Takeuchi A, Saito T. CD4 CTL, a Cytotoxic Subset of CD4+ T Cells, Their Differentiation and Function. Frontiers in Immunology 2017; 8: 194.

Mittrücker H, Visekruna A, Huber M. Heterogeneity in the differentiation and function of CD8+ T cells. Archivum Immunologiae et Therapiae Experimentalis (Warsz) 2014; 62(6): 449-458.

Wang Y, Ning Y, Ding Y. Research progress on chemical constituents and pharmacological action of Schisandra chinensis. Information on Traditional Chinese Medicine 2023; 40(7): 82-85+90.

Wang Z, Wang J. Research progress on the pharmacological effects of arctigenin. China Medical Herald 2018; 15(32): 50-53.

Jiang F, Qin Li, Yang L, et al. Effect of Suhuang cough capsule combined with montelukast sodium on traditional Chinese medicine syndromes and immune function in patients with postinfectious cough. Hebei Journal of Traditional Chinese Medicine 2023; 45(5): 747-750+755.

Yan D, Ou L, Li Y, et al. Clinical effects of Suhuang Zhike Capsules on patients with acute exacerbation of chronic obstructive pulmonary disease. Chinese Traditional Patent Medicine 2023; 45(5): 1493-1497.

Mao J, Xiao H, Zhai X, et al. Treating Sequelae of Pelvic Inflammatory Disease of Damp-Heat Stasis Type with Hufu Copper Bian Scraping Therapy. Journal of the Chinese Medical Association 2022; 37(7): 1557-1560.

He X, Qin M, Tang X, et al. Clinical Study of Scraping Therapy Combined with Ginger-separated Moxibustion for Improve Immune Function after Chemotherapy of Colorectal Cancer. Journal of Sichuan of Traditional Chinese Medicine 2021; 39(12): 217-220.