Research Progress on Cangfu Daotan Pills in the Treatment of Polycystic Ovary Syndrome
DOI:
https://doi.org/10.62767/jecacm601.5826Keywords:
polycystic ovary syndrome, Cangfu Daotan Pills, sex hormones, metabolic disorders, endometrial blood flow, varian granulosa cell autophagyAbstract
Polycystic ovary syndrome (PCOS) is a heterogeneous disease characterized clinically by high androgen levels, persistent anovulation, and polycystic ovarian changes, whose incidence has been on the rise, becoming a major factor in anovulatory infertility among women of childbearing age. Cangfu Daotan Pills, as a traditional Chinese medicine compound formula, has the effects of dispelling dampness and phlegm, tonifying the kidney, promoting blood circulation, and removing blood stasis, and can regulate physiological functions of the body through multiple targets and pathways. This study reviews the research progress on the treatment of PCOS with Cangfu Daotan Pills, exploring its mechanisms of action, which significantly improve ovarian function and promote ovulation in PCOS patients by regulating sex hormone levels, improving the inflammatory microenvironment, correcting metabolic disorders, regulating uterine blood flow, and reducing autophagy of ovarian granulosa cells, thus increasing pregnancy rates. Additionally, the main active ingredients of Cangfu Daotan Pills are summarized, highlighting their therapeutic effects through the regulation of multiple key targets and signaling pathways. In terms of clinical application, Cangfu Daotan Pills used alone, in combination with Western medicine, or in conjunction with external treatments has shown good efficacy and low side effects. Future research is expected to further explore the efficacy principles of Cangfu Daotan Pills through multidisciplinary approaches, providing a scientific basis for the refinement of clinical treatment plans and the development of new drugs.
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