Advancing Cardiovascular Health: Unveiling the Role of Traditional and Natural Medicine

Authors

  • Chun-Han Cheng Department of Medical Education, Linkou Chang Gung Memorial Hospital, 33305 Taoyuan City, Taiwan, China Author
  • Ju-Chi Liu Department of Cardiology, Shuang Ho Hospital, Ministry of Health and Welfare, Taipei Medical University, 23561 New Taipei City, Taiwan, China; Division of Cardiology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, 11002 Taipei City, Taiwan, China Author
  • Huan-Yuan Chen Institute of Biomedical Sciences, Academia Sinica, 11529 Taipei City, Taiwan, China Author
  • Chun-Chao Chen Department of Cardiology, Shuang Ho Hospital, Ministry of Health and Welfare, Taipei Medical University, 23561 New Taipei City, Taiwan, China; Division of Cardiology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, 11002 Taipei City, Taiwan, China Author
  • Jin-Jer Chen Institute of Biomedical Sciences, Academia Sinica, 11529 Taipei City, Taiwan, China; Division of Cardiology, Department of Internal Medicine and Graduate Institute of Clinical Medical Science, China Medical University Hospital, 404327 Taichung City, Taiwan, China Author
  • Wen-Rui Hao Department of Cardiology, Shuang Ho Hospital, Ministry of Health and Welfare, Taipei Medical University, 23561 New Taipei City, Taiwan, China; Division of Cardiology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, 11002 Taipei City, Taiwan, China Author
  • Tzu-Hurng Cheng Department of Biochemistry, School of Medicine, China Medical University, 404328 Taichung City, Taiwan, China Author

DOI:

https://doi.org/10.62767/jecacm504.4389

Keywords:

cardiovascular health, traditional medicine, natural remedies, holistic approach, integrative medicine

Abstract

In the quest for optimizing cardiovascular health, contemporary research increasingly explores the potential benefits of traditional and natural medicinal modalities. This paper provides insights into the therapeutic avenues offered by traditional medicine systems and natural remedies in cardiovascular care. Incorporating knowledge from ancient healing traditions like Ayurveda and Traditional Chinese Medicine (TCM) alongside contemporary research on the efficacy of natural compounds, the paper aims to elucidate their cardiovascular effects. Specifically, it examines the impact of lifestyle modifications, dietary supplements, and botanical extracts on cardiovascular health. Synthesizing evidence from clinical trials, preclinical studies, and traditional knowledge systems, the paper underscores the importance of integrating traditional and natural medicine practices with conventional medical interventions. This integration is vital for enhancing our understanding and management of cardiovascular diseases, contributing to more effective preventive strategies and optimized therapeutic outcomes in cardiovascular medicine.

References

Ding X, Ma X, Meng P, et al. Potential Effects of Traditional Chinese Medicine in Anti-Aging and Aging-Related Diseases: Current Evidence and Perspectives. Clinical Interventions in Aging 2024; 19: 681-693.

Hao P, Jiang F, Cheng J, et al. Traditional Chinese Medicine for Cardiovascular Disease: Evidence and Potential Mechanisms. Journal of the American College of Cardiology 2017; 69(24): 2952-2966.

Khan SU, Khan SU, Suleman M, et al. Natural Allies for Heart Health: Nrf2 Activation and Cardiovascular Disease Management. Current Problems in Cardiology 2024; 49(1): 102084.

Wang J, Zou J, Shi Y, et al. Traditional Chinese medicine and mitophagy: A novel approach for cardiovascular disease management. Phytomedicine 2024; 128: 155472.

Subbarayappa BV. The roots of ancient medicine: an historical outline. Journal of Biosciences 2001; 26(2): 135-143.

Liu HH, Nichols C, Zhang H. Understanding Yin-Yang Philosophic Concept Behind Tai Chi Practice. Holistic Nursing Practice 2023; 37(5): E75-E82.

Wu L, Chen W, Wang Z. Traditional Indian medicine in China: The status quo of recognition, development and research. Journal of Ethnopharmacology 2021; 279: 114317.

Ahmad SS, Ahmad K, Hwang YC, et al. Therapeutic Applications of Ginseng Natural Compounds for Health Management. International Journal of Molecular Sciences 2023; 24(24): 17290.

Lu M, Zhang L, Pan J, et al. Advances in the study of the vascular protective effects and molecular mechanisms of hawthorn (Crataegus anamesa Sarg.) extracts in cardiovascular diseases. Food & Function 2023; 14(13): 5870-5890.

Jiang Y, Cai Y, Han R, et al. Salvianolic acids and its potential for cardio-protection against myocardial ischemic reperfusion injury in diabetes. Frontiers in Endocrinology 2023; 14: 1322474.

Kumar V, Sharma N, Saini R, et al. Therapeutic potential and industrial applications of Terminalia arjuna bark. Journal of Ethnopharmacology 2023; 310: 116352.

White D. Healthy Uses for Garlic. Nursing Clinics of North America 2021; 56(1): 153-156.

Shahrajabian MH, Sun W. The Golden Spice for Life: Turmeric with the Pharmacological Benefits of Curcuminoids Components, including Curcumin, Bisdemethoxycurcumin, and Demethoxycurcumin. Current Organic Synthesis 2024; 21(5): 665-683.

Nauman E. Native American medicine and cardiovascular disease. Cardiology in Review 2007; 15(1): 35-41.

Chevinsky J, Chirumamilla S, Caswell S, et al. Clinical Preventive Medicine, Integrative Medicine, and Lifestyle Medicine: Current State and Future Opportunities in the Development of Emerging Clinical Areas. AJPM Focus 2024; 3(1): 100166.

Mohammed SAD, Hanxing L, Fang L, et al. Integrated Chinese herbal medicine with Western Medicine versus Western Medicine in the effectiveness of primary hypertension treatment: A systematic review and meta-analysis of randomized controlled trials. Journal of Ethnopharmacology 2023; 300: 115703.

Gyawali D, Vohra R, Orme-Johnson D, et al. A Systematic Review and Meta-Analysis of Ayurvedic Herbal Preparations for Hypercholesterolemia. Medicina 2021; 57(6): 546.

Roshanzamir S, Haririan Y, Ghaderpanah R, et al. Investigation of the Effects of Acupuncture on Post-Operative Chest Pain after Open Heart Surgery. Journal of Acupuncture and Meridian Studies 2023; 16(4): 133-138.

Wu K, Wan M, Zhou H, et al. Mindfulness-based stress reduction combined with early cardiac rehabilitation improves negative mood states and cardiac function in patients with acute myocardial infarction assisted with an intra-aortic balloon pump: a randomized controlled trial. Frontiers in Cardiovascular Medicine 2023; 10: 1166157.

Asamoah GD, Khakpour M, Carr T, et al. Exploring Indigenous Traditional Healing programs in Canada, Australia, and New Zealand: A scoping review. Explore 2023; 19(1): 14-25.

Raina K, Kumari R, Thakur P, et al. Mechanistic role and potential of Ayurvedic herbs as anti-aging therapies. Drug Metabolism and Personalized Therapy 2023; 38(3): 211-226.

Butnariu M, Fratantonio D, Herrera-Bravo J, et al. Plant-food-derived Bioactives in Managing Hypertension: From Current Findings to Upcoming Effective Pharmacotherapies. Current Topics in Medicinal Chemistry 2023; 23(8): 589-617.

Al-Khayri JM, Sahana GR, Nagella P, et al. Flavonoids as Potential Anti-Inflammatory Molecules: A Review. Molecules 2022; 27(9): 2901.

Jones PJ, Demonty I, Chan YM, et al. Fish-oil esters of plant sterols differ from vegetable-oil sterol esters in triglycerides lowering, carotenoid bioavailability and impact on plasminogen activator inhibitor-1 (PAI-1) concentrations in hypercholesterolemic subjects. Lipids in Health and Disease 2007; 6: 28.

Zhang LY, Ding L, Shi HH, et al. Eicosapentaenoic acid in the form of phospholipids exerts superior anti-atherosclerosis effects to its triglyceride form in ApoE(-/-) mice. Food & Function 2019; 10(7): 4177-4188.

Froldi G, Ragazzi E. Selected Plant-Derived Polyphenols as Potential Therapeutic Agents for Peripheral Artery Disease: Molecular Mechanisms, Efficacy and Safety. Molecules 2022; 27(20): 7110.

Li X, Yu T, Jiang Q, et al. The Efficacy of Traditional Chinese Herbal Medicine Across Multiple Cardiovascular Diseases: An Umbrella Review of Systematic Reviews of Randomized Controlled Trials. Journal of Cardiovascular Pharmacology 2024; 83(4): 340-352.

Zhang M, Zhu Y, Wang J, et al. Association between acupuncture and grade 1 hypertension: A systematic review and meta-analysis. Complementary Therapies in Clinical Practice 2022; 49: 101649.

Ge B, Chen H, Liao X. The effect of mind-body exercise on blood pressure in middle-aged and elderly patients with hypertension: A protocol for a systematic review and meta-analysis. Medicine 2021; 100(25): e26452.

Yang Y, Li X, Chen G, et al. Traditional Chinese Medicine Compound (Tongxinluo) and Clinical Outcomes of Patients With Acute Myocardial Infarction: The CTS-AMI Randomized Clinical Trial. JAMA 2023; 330(16): 1534-1545.

Martinez-Gonzalez MA, Gea A, Ruiz-Canela M. The Mediterranean Diet and Cardiovascular Health. Circulation Research 2019; 124(5): 779-798.

Koch E, Malek FA. Standardized extracts from hawthorn leaves and flowers in the treatment of cardiovascular disorders--preclinical and clinical studies. Planta Medica 2011; 77(11): 1123-1128.

Asghar A, Qasim M, Noor F, et al. Systematic elucidation of the multi-target pharmacological mechanism of Terminalia arjuna against congestive cardiac failure via network pharmacology and molecular modelling approaches. Natural Product Research 2023; 37(22): 3733-3740.

DuBroff R, Lad V, Murray-Krezan C. A Prospective Trial of Ayurveda for Coronary Heart Disease: A Pilot Study. Alternative Therapies in Health and Medicine 2015; 21(5): 52-62.

Lee MM, Shen JM. Dietary patterns using Traditional Chinese Medicine principles in epidemiological studies. Asia Pacific Journal of Clinical Nutrition 2008; 17(S1): 79-81.

Aggarwal M, Bozkurt B, Panjrath G, et al. Lifestyle Modifications for Preventing and Treating Heart Failure. Journal of the American College of Cardiology 2018; 72(19): 2391-2405.

Gencer B, Djousse L, Al-Ramady OT, et al. Effect of Long-Term Marine ɷ-3 Fatty Acids Supplementation on the Risk of Atrial Fibrillation in Randomized Controlled Trials of Cardiovascular Outcomes: A Systematic Review and Meta-Analysis. Circulation 2021; 144(25): 1981-1990.

Baird R. Systematic reviews and meta-analytic techniques. Seminars in Pediatric Surgery 2018; 27(6): 338-344.

Chung VCH, Wong CHL, Zhong CCW, et al. Traditional and complementary medicine for promoting healthy ageing in WHO Western Pacific Region: Policy implications from utilization patterns and current evidence. Integrative Medicine Research 2021; 10(1): 100469.

Von Schoen-Angerer T, Manchanda RK, Lloyd I, et al. Traditional, complementary and integrative healthcare: global stakeholder perspective on WHO's current and future strategy. BMJ Global Health 2023; 8(12): e013150.

Klein-Junior LC, de Souza MR, Viaene J, et al. Quality Control of Herbal Medicines: From Traditional Techniques to State-of-the-art Approaches. Planta Medica 2021; 87(12-13): 964-988.

Sarma N, Upton R, Rose U, et al. Pharmacopeial Standards for the Quality Control of Botanical Dietary Supplements in the United States. Journal of Dietary Supplements 2023; 20(3): 485-504.

Hung YL, Leung SS, Chiu SP, et al. Perceptions about traditional Chinese medicine use among Chinese breast cancer survivors: A qualitative study. Cancer Medicine 2023; 12(2): 1997-2007.

Liu Z, Jiang Z, Fang H, et al. Perception, Price and Preference: Consumption and Protection of Wild Animals Used in Traditional Medicine. PLoS One 2016; 11(3): e0145901.

Bautista-Valarezo E, Duque V, Verhoeven V, et al. Perceptions of Ecuadorian indigenous healers on their relationship with the formal health care system: barriers and opportunities. BMC Complement Medicine Therapies 2021; 21(1): 65.

Steel A, Adams J. The interface between tradition and science: naturopaths' perspectives of modern practice. Journal of Alternative and Complementary Medicine 2011; 17(10): 967-972.

Pullen SJ, Herman AR, Lange BC, et al. Towards a better understanding of attitudes and beliefs held by traditional healers and recipients of traditional medicine concerning mental health conditions in post-conflict Liberia: a qualitative investigation. African Health Sciences 2021; 21(3): 1396-1409.

Akol A, Moland KM, Babirye JN, et al. "We are like co-wives": Traditional healers' views on collaborating with the formal Child and Adolescent Mental Health System in Uganda. BMC Health Services Research 2018; 18(1): 258.

Van Os J, Scheepers F, Milo M, et al. "It has to be better, otherwise we will get stuck." A Review of Novel Directions for Mental Health Reform and Introducing Pilot Work in the Netherlands. Clinical Practice and Epidemiology in Mental Health 2023; 19: e17450179271206.

Miranda AMA, Janbandhu V, Maatz H, et al. Single-cell transcriptomics for the assessment of cardiac disease. Nature Reviews Cardiology 2023; 20(5): 289-308.

Petek BJ, Al-Alusi A, Moulson N, et al. Consumer Wearable Health and Fitness Technology in Cardiovascular Medicine: JACC State-of-the-Art Review. Journal of the American College of Cardiology 2023; 82(3): 245-264.

Zhang J, Wehrle E, Rubert M, et al. 3D Bioprinting of Human Tissues: Biofabrication, Bioinks, and Bioreactors. International Journal of Molecular Sciences 2021; 22(8): 3971.

Ogungbe O, Longenecker CT, Beaton A, et al. Advancing Cardiovascular Health Equity Globally Through Digital Technologies. Journal of the American Heart Association 2024; 13(2): e031237.

Gao L, Cao M, Li JQ, et al. Traditional Chinese Medicine Network Pharmacology in Cardiovascular Precision Medicine. Current Pharmaceutical Design 2021; 27(26): 2925-2933.

Diab A, Dastmalchi LN, Gulati M, et al. A Heart-Healthy Diet for Cardiovascular Disease Prevention: Where Are We Now? Vascular Health and Risk Management 2023; 19: 237-253.

Weldy CS, Ashley EA. Towards precision medicine in heart failure. Nature Reviews Cardiology 2021; 18(11): 745-762.

Yan Q. The Yin-Yang Dynamics in Cardiovascular Pharmacogenomics and Personalized Medicine. Methods in Molecular Biology 2022; 2547: 255-266.

Mensah GA, Fuster V, Murray CJL, et al. Global Burden of Cardiovascular Diseases and Risks, 1990-2022. Journal of the American College of Cardiology 2023; 82(25): 2350-2473.

Pant A, Chew DP, Mamas MA, et al. Cardiovascular Disease and the Mediterranean Diet: Insights into Sex-Specific Responses. Nutrients 2024; 16(4): 570.

Law SK, Wang Y, Lu X, et al. Chinese medicinal herbs as potential prodrugs for obesity. Frontiers in Pharmacology 2022; 13: 1016004.

Published

2024-10-08

Data Availability Statement

The analyzed data sets generated during the study are available from the corresponding author on reasonable request.

Issue

Section

Review

Similar Articles

1-10 of 81

You may also start an advanced similarity search for this article.

Most read articles by the same author(s)

<< < 1 2 3 4 5 6 7 8 9 > >>