Research Progress on Pharmacological and Toxicological Effects of Bavachin

Yeqing Jiang; Shiyu Hu; Jiaman Shen; Dongling Shi

doi:10.62767/jecacm504.2748

Authors

Yeqing Jiang Hangzhou Fuyang Hospital of Traditional Chinese Medicine, 311400 Hangzhou, Zhejiang, China Author
Shiyu Hu School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, 310053 Hangzhou, Zhejiang, China Author
Jiaman Shen School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, 310053 Hangzhou, Zhejiang, China Author
Dongling Shi Academy of Chinese Medical Sciences, Zhejiang Chinese Medical University, 310053 Hangzhou, Zhejiang, China Author

DOI:

https://doi.org/10.62767/jecacm504.2748

Keywords:

bavachin, estrogen-like, anti-inflammatory, anti-tumor, immunoregulatory, toxicology

Abstract

Objective: To analyze and summarize the latest research progress regarding pharmacological and toxicological effects of bavachin. Methods: Through retrieval of all bavachin-related reports on pubmed, CNKI, Wanfang database and other databases, the pharmacologic and toxicological effects of bavachin were sorted out and concluded accordingly. Results: The study showed that bavachin had a wide range of pharmacological activities, including estrogen-like, anti-inflammatory, anti-tumor, immunoregulatory, anti-diabetes and its complications effects. The toxicological effects of bavachin were mainly manifested in three aspects: hepatotoxicity, reproductive toxicity and nephrotoxicity. Conclusions: Bavachin has the characteristics of multi-function and multi-target monomer similar to traditional Chinese medicine, and broad application prospects, but also has certain toxicological effects. How to avoid toxicity, as well as enhance strengths and avoid weaknesses is the direction of development and utilization of bavachin. This review provides reference for further development and utilization of bavachin.

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