Therapeutic Effect of Traditional Chinese Medicine Decoction Combined with Cetirizine on Allergic Rhinitis of Kidney-Yang Deficiency Type

Abstract

Objective To explore the therapeutic effect of traditional Chinese medicine decoction combined with cetirizine on allergic rhinitis (AR) of kidney-Yang deficiency type. Methods A total of 96 patients with AR of kidney-Yang deficiency type treated in our hospital from Jul. 2014 to Jun. 2018 were selected and randomly divided into the Western medicine group (n=32), traditional Chinese medicine group (n=32) and combined Chinese and western medicine group (n=32) according to the random number table method, the patients of three groups were orally administrated cetirizine, warming Yang and tonifying Qi and treating sneezing decoction, and the combination of warming Yang and tonifying Qi and treating sneezing decoction and cetirizine, respectively. The total clinical effective rate, visual analog scale (VAS) scores before and after treatment, rhinoconjunctivitis quality of life questionnaire (RQLQ), TCM syndrome scores, and adverse effects were compared among the three groups. Results The total effective rate of the combined Chinese and Western medicine group was significantly higher than that of the Western medicine group and the traditional Chinese medicine group (P<0.05); After treatment, VAS, RQLQ and TCM syndrome scores of each group were significantly lower than those before treatment (P<0.05). The VAS, RQLQ and TCM syndrome scores in the combined Chinese and Western medicine group were significantly lower than those in the Western medicine group and the traditional Chinese medicine group (P<0.05); There was no significant difference in the incidence of adverse reactions between the traditional Chinese medicine group and the combined Chinese and Western medicine group (P>0.05), however, the incidence of adverse reactions in these two groups was significantly lower than that in the Western medicine group (P<0.05). Conclusion The effect of traditional Chinese medicine decoction combined with cetirizine on AR of kidney-Yang deficiency type was remarkable, and the adverse effects was few, which is worthy of clinical promotion.