Curative Effect of Xiangsha Liujunzi Decoction Combined with Weifuchun Tablet in Functional Dyspepsia

Abstract

Background: Our study aims to investigate the curative effect of Xiangsha Liujunzi Decoction combined with Weifuchun Tablet in functional dyspepsia. Methods: 45 patients with functional dyspepsia treated with Xiangsha Liujunzi Decoction combined with Weifuchun Tablet for 8 weeks from February 2022 to February 2023 in our hospital were selected into the observation group, and 45 patients with functional dyspepsia treated with Weifuchun tablet for 8 weeks were selected into control group during the same period. The clinical efficacy and adverse reactions of the two groups were compared, and the changes of TCM symptom score, gastric dynamics parameters, and inflammatory factor (CRP, TNF-α, and IL-6) levels in serum before and after treatment were observed. Results: The total effective rate of clinical efficacy in observation group was significantly higher than that in control group (p < 0.05). After treatment, the levels of TCM symptom score, half-empty time, 2 h retention rate, C-reactive protein, tumor necrosis factor-α, and Interleukin-6 in both groups were obviously reduced, and those in the observation group was visibly lower than those in the control group (p < 0.05). The emptying rate in the two groups was strikingly increased, and that in the observation group was remarkably higher than that in the control group (p < 0.05). There was no significant difference in the occurrence of diarrhea, vomiting, and nausea between the two groups (p > 0.05). Conclusion: Xiangsha Liujunzi Decoction combined with Weifuchun Tablet has a good clinical effect in the treatment of patients with functional dyspepsia, which can alleviate clinical symptoms, improve gastric motility, reduce inflammation, and has good safety.