Analysis on Therapeutic Effect of Biling Weitong Granules Combined with Pantoprazole on Patients with Gastroesophageal Reflux Disease of Qi Stagnation and Phlegm Retention Type

Abstract

Aim: This study is designed to unravel the therapeutic effect of Biling Weitong granules (BWG) combined with pantoprazole on patients with gastroesophageal reflux disease (GERD) of qi stagnation and phlegm retention type. Methods: 60 patients with GERD of qi stagnation and phlegm retention type, who were treated in our hospital from January 2022 to June 2023 and received BWG combined with pantoprazole, were perceived as combination group. Meanwhile, 45 patients treated with BWG were set as BWG group and 75 patients administrated with pantoprazole were constructed as pantoprazole group. The treatment in the three groups lasted for 2 months. The clinical therapeutic efficacy, symptom score, gastroesophageal reflux disease questionnaire (GERDQ) score and adverse reactions were recorded and compared among the three groups. Results: After treatment, the symptom score and GERDQ score were reduced in the three groups, and the two scores were the lowest in combination group by comparison (p < 0.05). Among the three groups, the clinical total effective rate was the highest in combination group (p < 0.05), and the incidence of adverse reactions had no obvious differences (p > 0.05). Conclusion: BWG combined with pantoprazole can effectively improve GERD of qi stagnation and phlegm retention type, which relieves patients’ clinical symptoms without severe adverse reactions.