Therapeutic Effect of Neuroendoscopic Removal of Hematoma from Elderly Patients with HCH and Its impact on Neurological Functions and Inflammatory Factors

Abstract

Objective To explore the effect of neuroendoscopic hematoma removal in elderly patients with hypertensive intracerebral hemorrhage (HIH) and its impact on neurological functions and inflammatory factors. Method A total of 66 patients with HIH who attended our hospital from Jan. 2019 to Mar. 2020 for treatment were selected as the research objects. The patients were divided into control group and observation group by random number table method, with 40 cases in each group. The control group was treated with small bone window, while the observation group was treated with neuroendoscopic removal of haematoma. The clinical effect, nerve defect score and inflammatory factor level of the two groups were compared. Result Compared with the control group, the operation time was shorter, intraoperative bleeding volume was smaller and hematoma clearance rate was higher in the observation group (P<0.05). After treatment, the neurological deficit score of the two groups was significantly lower than that before treatment (P<0.05), and the NDS of the observation group was noticeably lower than that of the control group (P<0.05). After treatment, moreover, the levels of tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and hypersensitive C-reactive protein (hs-CRP) in the two groups were noticeably lower than those before treatment (P<0.05), and the levels of TNF-α IL-6 and hs-CRP in the observation group were greatly lower than those in the control group (P<0.05). Conclusion Neuroendoscopic removal of haematoma could effectively improve neurological functions and reduce inflammatory factors in elderly patients with HIH.