Effect of Local Mild Hypothermia Therapy Combined with Early Continuous Nursing on Nerve Function and Inflammatory Factors in Patients with Subarachnoid Hemorrhage

Xuan Lv; Hua Shan; Suijun Zhu

doi:10.62767/dbm501.0912

Authors

Xuan Lv Department of Neurosurgery, The First People's Hospital of Linping District, Hangzhou, 311100 Hangzhou, Zhejiang, China Author
Hua Shan Department of Medical Affairs, The First People's Hospital of Linping District, Hangzhou, 311100 Hangzhou, Zhejiang, China Author
Suijun Zhu Department of Neurosurgery, The First People's Hospital of Linping District, Hangzhou, 311100 Hangzhou, Zhejiang, China Author

DOI:

https://doi.org/10.62767/dbm501.0912

Keywords:

local mild hypotherm, early continuous nursing, subarachnoid hemorrhage, nerve function, inflammatory factors

Abstract

Objective: To investigate the effect of local mild hypothermia combined with early continuous nursing on nerve function and inflammatory factors in patients with subarachnoid hemorrhage. Methods: 40 patients with subarachnoid hemorrhage receiving local mild hypothermia combined with early continuous nursing in our hospital from January 2023 to December 2023 were included as the combination group, and meanwhile 40 patients with subarachnoid hemorrhage receiving early continuous nursing were included as the control group. Neurological function, levels of inflammatory factors, cerebral artery blood flow velocity and psychological state were compared between the two groups before and after treatment, and complications were recorded between the two groups during treatment. Results: After treatment, National Institutes of Health Stroke Scale score, anterior blood flow velocity in cerebral artery, posterior cerebral artery and middle cerebral artery, interleukin-8, high-sensitivity C-reactive protein, tumor necrosis factor-α, and Hamilton depression and anxiety scores were decreased in both groups, and the decrement was more apparent in the combination group than the control group (p < 0.05). The Glasgow outcome score was elevated after treatment in both groups, which was higher in the combination group than the control group (p < 0.05). The complication rate in combination group was lower than that in control group (p < 0.05). Conclusion: Local mild hypothermia combined with early continuous nursing can effectively improve the nerve function and cerebral artery blood flow velocity, reduce the level of inflammatory factors, and regulate the psychological state of patients with subarachnoid hemorrhage under good safety.

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