Effect of Yangxue Qingnao Pills Combined with Plavix on Blood Coagulation Function and Barther Index in Patients with TIA

Abstract

Objective To explore the clinical efficacy of treatment of Yangxue Qingnao pills combined with Plavix in patients with transient ischemic attack (TIA), and the effect on blood coagulation function of patients and Barther index. Methods A total of 116 cases of TIA patients in our hospital from Jan. 2018 to Aug. 2020 were randomly divided into the control group (n=58) and the observation group (n=58). With the basic regular treatment of the both groups, the control group was treated with Plavix, the observation group was treated with Yangxue Qingnao pills combined with Plavix. The clinical efficacy, blood coagulation function, Barther index and incidence of adverse reactions of the both groups were compared before and after treatment. Results The total effective rate was obviously higher in the observation group than that in the control group (P<0.05); The prothrombin time (PT), activated partial thromboplastin time (APTT) and Barther index score of both groups after treatment were obviously increased in comparison with those before treatment (P<0.05), and the observation group was obviously increased in comparison with those in the control group (P<0.05); The level of fibrinogen (FIB) of both groups after treatment was obviously decreased in comparison with that before treatment (P<0.05), and the observation group was obviously decreased in comparison with that in the control group (P<0.05); The incidence rate of adverse reactions of the observation group and the control group were 8.62% and 12.07% respectively, no significant difference was observed in the incidence rate of adverse reactions between both groups (χ²=0.372, P=0.542). Conclusion The combination of Yangxue Qingnao pills and Plavix has shown significant efficacy in treating patients with TIA, improving their blood coagulation function and neurological function.