Etiological Characteristics and Related Factors of Intracranial Infection after Craniocerebral Trauma Surgery

Abstract

Objective To explore etiological characteristics and related factors contributing to intracranial infection after craniocerebral trauma surgery. Methods According to whether postoperative intracranial infection occurred, 293 cases of patients with craniocerebral trauma admitted to our hospital from March 2016 to October 2019 were divided into observation group (n = 78) and control group (n = 215). The pathologic features and related risk factors of intracranial infection after traumatic brain injury were observed and analyzed from secretion culture of all patients. Results There were 97 strains of pathogens in the blood culture of the observation group,with Pseudomonas aeruginosa and Escherichia coli accounting for 24.74% and 18.56%, respectively (P<0.05). The postoperative prevention of antibiotic use, postoperative albumin level and postoperative use of hormones were all independent risk factors for intracranial infection after craniocerebral trauma (P<0.05). Conclusion Traumatic brain injury in patients with intracranial infection was influenced by a variety of factors. Medical workers should minimize the operation time to prevent cerebrospinal fluid incision leakage, postoperative catheter drainage, postoperative preventive use of antibiotics. Moreover, improving postoperative albumin and reducing the use of hormones after surgery, carefully paying more attention to patients more attention are all important in lowering the possibility of developing intracranial infection.