Clinical Efficacy of Shenqi Jiangtang Granules Combined with Acupuncture on Type 2 Diabetic Peripheral Neuropathy with Dual Deficiency of Qi and Yin

Abstract

Aim: This study is devoted to anatomizing the clinical efficacy of Shenqi Jiangtang granules combined with acupuncture on type 2 diabetic peripheral neuropathy (T2DPN) with dual deficiency of qi and yin. Methods: 48 patients with T2DPN and dual deficiency of qi and yin, who were admitted to our hospital and received treatment of Shenqi Jiangtang granules combined with acupuncture from April, 2021 to April, 2023 (termed observation group). Meanwhile, the other 48 patients with the same disease and symptoms receiving acupuncture treatment were set as a control group. Both groups were treated for 3 months. The traditional Chinese medicine (TCM) symptom scores, pancreas islet function indicators, nerve conduction level and adverse reactions during treatment were compared between the two groups. Results: The total clinical effective rate (93.75%) was higher in observation group than control group (79.17%) (p < 0.05). After treatment, the TCM symptom scores, fasting insulin level, and insulin resistance index were decreased in the two group, and the decreasing trend was more apparent in observation group (p < 0.05). Through treatments, the sensory nerve conduction velocity (SNCV) and motor nerve conduction velocity (MNCV) of median nerve, posterior tibial nerve and common peroneal nerve were elevated (p < 0.05), and the velocity was faster in observation group than control group (p < 0.05). Notably, no particularly severe adverse reactions were detected in the two groups during treatment. Conclusion: Shenqi Jiangtang granules combined with acupuncture has higher therapeutic efficacy on T2DPN with dual deficiency of qi and yin, which can help patients relieve clinical symptoms, improve pancreas islet functions and mitigate nerve injury, with high safety.