Clinical Study of Huaier Granule Combined with Auricular Point Seed Pressing in Postoperative Treatment of Primary Liver Cancer Patients Undergoing Transcatheter Arterial Chemoembolization

Authors

  • Guotao Liu The First Affiliated Hospital of Zhejiang Chinese Medical University, Zhejiang Provincial Hospital of Traditional Chinese Medicine, Qiantang Branch, 310018 Hangzhou, Zhejiang, China Author
  • Xiaodi Shen The First Affiliated Hospital of Zhejiang Chinese Medical University, Zhejiang Provincial Hospital of Traditional Chinese Medicine, Qiantang Branch, 310018 Hangzhou, Zhejiang, China Author

Keywords:

auricular point seed pressin, Huaier granule, primary liver cancer, liver function

Abstract

Background: This study aims to explore the curative effect of Huaier granule combined with auricular point seed pressing on primary liver cancer after transcatheter arterial chemoembolization. Methods: Clinical data of 80 patients with primary liver cancer treated in our hospital from March 2022 to March 2023 were retrospectively analyzed. 40 patients receiving Huaier granule combined with auricular point seed pressing therapy after transcatheter arterial chemoembolization were assigned into the observation group, and 40 patients receiving auricular point seed pressing therapy after transcatheter arterial chemoembolization were allocated into the control group. The clinical efficacy in the two groups was compared, and the effect of different treatment methods on traditional Chinese medicine (TCM) symptom score, liver function indicators measured using an automatic biochemical analyzer, including serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin (TBIL) and albumin (ALB), and quality of life of patients was observed, and the safety was analyzed. Results: The total remission rate in observation group was significantly higher than that in control group (p < 0.05). After treatment, the TCM symptom score and the levels of ALT, AST, serum TBIL and ALB in the two groups were significantly decreased (p < 0.05). The levels of abovementioned indexes in observation group were obviously lower than those in control group (p < 0.05). Quality of life scores in both groups were apparently elevated (p < 0.05), and the scores in observation group were distinctly higher than those in control group (p < 0.05). There was no statistical significance in the incidence of adverse reactions between the two groups (p > 0.05). Conclusion: Huaier granule combined with auricular point seed pressing in the treatment of primary liver cancer after transcatheter arterial chemoembolization may have a good curative effect, which can improve the symptoms of TCM and help to recover patients’ liver function and quality of life, with a high safety.

Published

2023-10-21

Issue

Section

Original Research